The Metabolism and Function of Pantothenic Acid

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The metabolism of pantothenic acid.

The formulation of this pathway was based on: (a) the finding that cysteine supplies the sulfur-containing moiety of CoA (3,4); (b) the activities of pantetheine and pantothenylcysteine as growth factors for Acetobacter suboxydans (4-6) and Lactobacillus helveticus (7); (c) the presence of enzymes in these two organisms and also in Lactobacillus bulgur&s which decarboxylate pantothenylcysteine ...

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Carbohydrate metabolism and adrenal cortical function in the pantothenic acid-deficient rat.

A relationship between pantothenic acid and the adrenal gland has been evident since the earliest work with this vitamin was done. Morgan and Simms (1) found pathologic changes in the adrenals of rats on diets free from “filtrate factor,” and reported (2) that the achromotrichia of rats maintained on these diets could be at least partly reversed by extracts of the thyroid and of the adrenal cor...

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Antagonism of L(-)pantothenic acid on lipid metabolism in animals.

The inhibition rate of L(-)pantothenate as an antagonist of D(+)pantothenate was discussed from the viewpoint of growth and lipid metabolism. The growth rate of mice given pantothenate-deficient diets containing L(-)pantothenate (300 mg per 100g diet) was markedly decreased, and such pantothenate-deficient symptoms as "spectacle eyes" appeared. However, it was recovered by the simultaneous addi...

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ژورنال

عنوان ژورنال: Proceedings of the Nutrition Society

سال: 1953

ISSN: 0029-6651,1475-2719

DOI: 10.1079/pns19530017